Naprelan: Naproxen controlled-release belongs to the class of medications called nonsteroidal anti-inflammatory drugs (NSAIDs). It is used to reduce the pain and swelling associated with rheumatoid arthritis and osteoarthritis. It works by reducing the amount of certain chemicals produced by your body that cause pain and swelling. Click here for Full Prescribing Information, including Boxed WARNING and Medication Guide. Naproxen sodium is an odorless crystalline powder, white to creamy in color. It is soluble in methanol and water. NAPRELAN Tablets contain 412.5 mg, 550 mg, or 825 mg of naproxen sodium, equivalent to 375 mg, 500 mg, and 750 mg of naproxen, and 37.5 mg, 50 mg, and 75 mg sodium respectively. NAPRELAN 500: white, capsule-shaped tablet with “N” on one side and “500” on the reverse. Each Each tablet contains 550 mg naproxen sodium equivalent to 500 mg naproxen. Find patient medical information for Naprelan CR Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. For naproxen controlled-release tablet (eg, Naprelan®) dosage form: For rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis: Adults—At first, 750 milligrams (mg) (taken as one 750 mg or two 375 mg tablets) or 1000 mg (taken as two 500 mg tablets) once a day. NAPRELAN prescription and dosage sizes information for physicians and healthcare professionals. Pharmacology, adverse reactions, warnings and side effects. Naprelan CR 500mg Tablets. Product Summary This product requires a valid prescription for shipment, please note that HealthWarehouse.com may not accept prescriptions faxed or emailed by patients. Naprelan 375: white, capsule-shaped tablet with “N” on one side and “375” on the reverse. Each tablet contains 412.5 mg naproxen sodium equivalent to 375 mg naproxen. Each tablet contains 412.5 mg naproxen sodium equivalent to 375 mg naproxen. NAPRELAN ® (naproxen sodium) CONTROLLED-RELEASE TABLETS. Equivalent to 375mg, 500mg and 750mg naproxen NAPRELAN ® Controlled-Release Tablets, 375mg, 500mg and 750mg.